In its pure state it is a white flake or powdered crystal. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. 1272/2008 [CLP] Extra labelling to displayExtra classification(s) to display Currently, SA is produced exclusively from alkaline pyrolysis of castor oil. The solubility of sebacic acid in subcritical water was investigated. Slightly soluble in water. This action is mediated by the OXER1 receptor on these cells. Sublimes slowly at 750 mm Hg when heated to melting point. 2. text.skipToContent text.skipToNavigation. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. [4,9] Poly( Ethylene - Find MSDS or SDS, a COA, data sheets and more information. Material Safety Data Sheet Sebacic acid sc-215843 Hazard Alert Code Key: EXTREME HIGH MODERATE LOW Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Sebacic acid STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. Response surface methodology was used to study the combined effects of the different parameters such as temperature, static and dynamic time to optimize the process conditions for the maximum solubility of sebacic acid. It is resolved in ethanol, ether and soluble slightly in water. Sebacic acid for synthesis. Bioaccumulation/ AccumulationNo information available. CAS 111-20-6, EC Number 203-845-5, chemical formula HOOC(CH���)���COOH. - Find MSDS or SDS, a COA, data sheets and more information. Incompatible with strong oxidizingagents, bases, reducing agents. Stable. An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. Gujarat India. CopyCopied, InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14) CopyCopied, CXMXRPHRNRROMY-UHFFFAOYSA-N Sebazinsaeure. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic acid Revision Date 18-Jan-2018 (Brachydanio rerio) Persistence and DegradabilitySoluble in water Persistence is unlikely based on information available. Degree of solubility in water: 1 g/l 20 °C: Solubility (very soluble in) Alcohol: Property Value Probability; Human Intestinal Absorption + 0.5731: Blood Brain Barrier + 0.7397: Caco-2 permeable-0.6412: P-glycoprotein substrate Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. 58 / Monday, March 26, 2012 / Rules and Regulations 10/12/2015 EN (English US) 2/5 First-aid Measures After Eye Contact: Rinse cautiously with water for several minutes. Bioaccumulation/ AccumulationNo information available. 77, No. SEBACIC ACID 1 Physical and Chemical Fuction: Molecular Formula: HOOC(CH2)8COOH Molecular Weight: 202.25 It is white powder crystal, slightly dissolves in water, completely dissolved in ethanol or ether, but not in benzene. May react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Sebacic acid Revision Date 18-Jan-2018 (Brachydanio rerio) Persistence and DegradabilitySoluble in water Persistence is unlikely based on information available. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. To detect the synergistic effect, solubilities of sebacic acid in 14.35 %, 36.97 %, 79.81 %, and 90.00 % mole fraction ethanol aqueous solution were determined to supplement our previous report. CB-839(Telaglenastat) inudces autophagy and has antitumor activity. DESCRIPTION & APPLICATIONS Sebacic Acid is a white flake or powdered crystal. SEBACIC ACID: ICSC: 1685: 1,10-Decanedioic acid 1,8-Octanedicarboxylic acid Decanedioic acid: April 2008 Sebacic acid is a derivative of castor oil.[2]. Sebacic acid is a derivative of castor oil. Mobility Will likely be mobile in the environment due to its water solubility. 2. Avoid contact with skin and eyes. Sebacic Acid Safety Data Sheet According to Federal Register / Vol. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:41865, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton, 295 deg C / 100 mm (400.5825 °C / 760 mmHg), 295 °C / 100 mm (400.5825 °C / 760 mmHg), 294.5 °C / 100 mmHg (399.9979 °C / 760 mmHg). Solubility Show More Product # Description 283258 Sebacic acid, 99%, 84809 Sebacic acid, ≥95.0% (GC), 8.00753 Sebacic acid, for synthesis, Sorry we cannot compare more than 4 products at a time. Sebacic acid is an alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. It is resolved in ethanol, ether and soluble slightly in water. SEBACIC ACID reacts exothermically to neutralize bases, both organic and inorganic. Sebacic Acid Skin Not Available Eyes Not Available Respiratory LC50 Inhalation - rat - > 4,500 mg/m3 Ingestion Not Available Carcinogenicity IARC No components of this product present at levels greater than or equal to 0.1% In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD) or glutaric aciduria type II (GAII) are a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. [2], It can also be obtained from decalin via the tertiary hydroperoxide, which gives cyclodecenone, a precursor to sebacic acid. Sebacic acid is an intermediate product of ��- oxidation of long-chain aliphatic acids. Sebacic acid (8CI) Registration dossier . Solubilities of sebacic acid in binary ethanol + water solvent mixtures were measured by the dynamic method using a laser monitoring observation technique at a … Sebacic acid (SA) is an aliphatic ten-carbon dicarboxylic acid (1,10-decanedioic acid) with a variety of industrial applications, including the production of plasticizers, lubricants, cosmetics, and plastics. Sebacic acid is a derivative of castor oil. Solubility results of sebacic acid were observed to be highly correlated with quadratic model according to analysis of variance. Applications Sebacic acid is used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics and candles. In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. Sebacic acid (8Cl) Registration dossier . Sebacic acid: Overview. Diesters of sebacic acid find various applications as plasticizers, solvents and lubricants. Sebacic acid, a 10 carbon containing dicarboxylic acid (DCA), is an important precursor in the production of nylon and polyamides (PAs), primarily PA-4,10 and PA-5,10 (Chung et al. 58 / Monday, March 26, 2012 / Rules and Regulations 10/12/2015 EN (English US) 2/5 First-aid Measures After Eye Contact: Rinse cautiously with water for several minutes.Remove contact lenses, if present and It is a white flake or powdered solid. We also Provide Trading Suppliers & Manufacture for 17265-14-4 SEBACIC ACID ��� Approximation models were employed for determining solubility of sebacic acid at elevated temperatures. Display Name: Sebacic acid EC Number: 203-845-5 EC Name: Sebacic acid CAS Number: 111-20-6 Molecular formula: C10H18O4 IUPAC Name: decanedioic acid Sebacic acid Description In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. PGS has a linear degradation profile via surface erosion, is completely bioresorbable, and its macroporous structure is well suited for cellular infiltration, paracrine signaling, and neotissue formation.81,82 Chen and colleagues reported that the elastomeric properties of PGS scaffolds render it a promising implant for use in myocardial tissue engineering applications. Sebacic acid is also found in other lipids that coat the skin surface. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic Acid was named from the Latin sebaceus (tallow candle) or … Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. Abstract. Regd. Sebacic acid is a normal urinary acid. In the industrial setting, sebacic acid and its homologues such as azelaic acid can be used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics, candles, etc. Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. Structure, properties, spectra, suppliers and links for: Sebacic acid, 111-20-6. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Registration dossier . Compared with short-chain aliphatic acid, sebacic acid is more suitable for the preparation of polyesters, as short-chain aliphatic acids always conduce to intramolecular condensation. & documentation regarding sebacic acid to its 5-oxo analog, i.e.5-oxo-6E,8Z-octadecaenoic acid ( 5-oxo-ODE ) EC 203-845-5! A COA, data sheets and more information neutralization generates a soluble.... [ 2 ] white flake or powdered crystal 390 005 ) and a sebacate ( 2- and! 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