2. The structures of the pons affected by the blockage are: The corticospinal tract which results in contralateral hemiparesis. Corneal reflex may be absent if there is pontine dysfunction. When the front part of the brain is affected both pupils become small but when other areas of the brain are affected one pupil dilates as the other constricts. Vertical gaze and convergence were preserved. 2007;9:41–5. A stroke could possibly affect cognitive function, language, pupil tone (unequal pupils), ability to swallow, and vital signs. Central pontine myelinolysis (CPM) is a neurological disorder that most frequently occurs after too rapid medical correction of sodium deficiency (hyponatremia). Early intervention can help prevent life … Figure 1: Computed tomography scan of the brain at admission revealed a large hematoma involving the basis and tegmentum of the pons predominantly on the left side. Left lateral pons c. Left ventral pons d. Right ventral pons. 2 No. Both the pupils become pinpoint when it is pontine … Many important nerves originate in the pons (Healthline 2018). Look through belongings for ID cards, medical alert cards/jewelry, cell phones, meds, and evidence of substances 2. Bilateral pinpoint pupils – mophine poisoning – pontine hemorrhage – organophosphates or eye drops (miotic) 18 Initial Exam Asymmetric pupils (anisocoria) – difference of 1mm or less and normal constriction may be normal – if the dilated pupil does not react … Basilar Artery Syndromes •Pontine Syndromes ... –Pinpoint pupils •Sensory –Not common, but may involve contralateral loss of light touch, … It’s more common in adults than in children. The brain stem serves as a connection between the brain and the body, coordinating motor control signals sent from the cerebrum to the spinal cord. Factors Determining the Outcome of Pontine Hemorrhage in the Absence of Surgical Intervention. The differential diagnosis of coma with small pupils includes: Non-toxicological causes. Brainstem stroke syndromes are a subtype of strokes which lead to ischemia of the structures of the brainstem. fixed dilated pupils, fixed eyes in midposition without any ocular movement, no corneal reflexes, and decerebrate rigidity with a posture of hyperextended and pronated extremities. He had had 2 episodes of complete bilateral horizontal conjugate gaze palsy with unimpaired consciousness lasting for 5 minutes each. Bell’s palsy is characterised by acute-onset unilateral facial paralysis of unknown aetiology. An Analysis of 35 Cases and Research in Prognostic Factors. If the pontine stroke was caused by a blood clot (ischemic stroke), then treatment will involve dissolving the clot to restore blood flow. A common treatment for ischemic pons stroke (i.e. pontine infarct) is tissue plasminogen activator (tPA), where an injection helps dissolve the clot. Posterior circulation ischaemic stroke is a clinical syndrome associated with ischaemia related to stenosis, in situ thrombosis, or embolic occlusion of the posterior circulation arteries—the vertebral arteries in the neck, the intracranial vertebral, basilar, and posterior cerebral arteries, and their branches (fig 1 ⇓ ). Knowledge of the anatomical basis of coma is essential for competent evaluation but must be combined with an understanding of the many, often multi-factorial, medical conditions that result in impaired consciousness. The direction of gaze deviation can be an important physical exam clue. A brainstem infarction (BSI) is a stroke that happens when blood cannot flow to your brainstem. Assessing the pupils Acutely widely dilated pupil on one side may be due to a unilateral space occupying lesion Bilateral abnormally constricted pupils may be due to opiates Bilaterally dilated pupils could be an intracranial catastrophe or due to sympathetic over activity i.e fear However, among general causes of stroke, the vertebrobasilar system accounts for 20%, more commonly the pons than the medulla or midbrain [2,3]. Though facial paralysis due to pontine infarct has been reported,3 pontine haemorrhage causing the same is extremely rare. A case of cervical dystonia from a pontine hemorrhage with subsequent progressive sternocleidomastoid muscle hypertrophy provides further support. Sign of a pontine tegmentum lesion. A pontine CVA affects the pons region of the brain stem, but to fully understand the role of the brain stem and the structure of the pons, a quick anatomy lesson is in order. The brain stem controls the central nervous system (CNS) and is situated along the base of the brain between the spinal cord and the two cerebral hemispheres. 4. digestion, salivation, perspiration, pupil dilation and contraction, urination). BACKGROUND: Little is known about stroke mechanisms in patients with fluctuating symptoms and the role of branch atherosclerotic disease. It can produce a classical clinical presentation as seen below. Site of the lesion: left medial pons. Fixed and pinpoint pupils suggests lower brainstem dysfunction in the area of the pons. Which ICH presents with dilated pupils A pontine cerebrovascular accident (also known as a pontine CVA or pontine stroke) is a type of ischemic stroke that affects the pons region of the brain stem. Brain complications such as pontine infarction and hemorrhaging lead to injuries of the brain causing stroke, illness and brain damage. A 64-year-old man presented with alternating exotropia and bilateral medial longitudinal fasciculus (MLF) syndrome known as wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) syndrome. A pontine stroke can be particularly devastating and may lead to paralysis and the rare condition known as … Pontine lesions (infarct or hemorrhage) classically involves sudden collapse with coma, pinpoint pupils and a spastic tetraparesis with brisk reflexes. The patient was diagnosed as having primary pontine hemor-rhage of the fulminant type, and she was treated con- Ask EMS for details about situation/scene 4. Pinpoint pupil is also seen in people suffering from brain hemorrhage. pinpoint-sized pupils in HE. Raymond syndrome (alternating abducens hemiplegia) is caused by a unilateral lesion of the ventromedial pons affecting the ipsilateral abducens nerve fascicles and corticospinal tract but sparing the facial nerve (Figs 17, 18). Pontine warning syndrome. Vertical gaze and convergence were preserved. His pupils were 4 mm and were equal and reactive to light. It carries a very poor prognosis. Primary Pontine Hemorrhage. Medial Pontine Syndrome. However, a stroke is a serious issue that is potentially life-threatening while Bell's palsy can be scary, but is a relatively benign condition. Causes of anisocoria range in seriousness from a normal, physiologic condition to one that is immediately life threatening. • Role of the pons in vergence movements is discussed. It also controls your breathing, heartbeat, blood pressure, balance, and eye movements. Only 10% of stroke survivors will recover completely. The diame-ter of the pupil is controlled by smooth muscle within Disconjugate disorders occurring in pontine stroke include INO, horizontal one-and-a-half syndrome, ocular bobbing (OB) and paralytic pontine esotropia. This is a case report of fluctuating pontine stroke with bilateral complete ophthalmoplegia due to branch atherosclerotic disease. A 63-year-old man with hypertension, diabetes mellitus, and dyslipidemia was seen with fluctuating right-sided weakness and dysarthria. Brainstem injuries. The brain stem (truncus cerebri) is located deep in the brains and provides the connection with the spinal cord. Raymond syndrome (alternating abducens hemiplegia) is caused by a unilateral lesion of the ventromedial pons affecting the ipsilateral abducens nerve fascicles and corticospinal tract but sparing the facial nerve (Figs 17, 18). Pupils were 3 mm and reactive to light. The symptoms resolve over a period of 6 months.1 2 Facial paralysis following pontine stroke is uncommon. Metabolic encephalopathy. Accurate determination of last known time when patient was at baseline is essential. 2018???:1-9. Inflammation and Horner's syndrome usually cause only one pupil to shrink, but not both. Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator. The brain stem is responsible for breathing, heart function, digestion and alertness. The rapid rise in sodium concentration is accompanied by the movement of small molecules and pulls water from brain cells. Marcus Gunn Pupil; The direct response to light in affected eye is decreased/absent; consensual response of affected eye to light in opposite eye is normal Vascular injury that reduces cerebral blood flow to specific region of brain causing neuro impairment. When oxygen cannot get to an area of the brain, tissue in that area may be damaged. Rambold H, Sander T, Neumann G, Helmchen C. Palsy of “fast” and “slow” vergence by pontine lesions. Rambold H, Sander T, Neumann G, Helmchen C. Palsy of “fast” and “slow” vergence by pontine lesions. Pontine stroke is a type of stroke that happens when the blood flow in the brain stem is disrupted. 17-20 Coma & small pupils – LITFL.com When stroke happens in the pons, which is the upper section of the brain stem, it’s called a pontine stroke. Wrong Way Eyes. According to the change in bilateral pupil size and alertness of this patient, it would be surmised that the lesion was most likely at the bilateral pons, with involvement of bilateral sympathetic tracts and the ascending reticular activating system(6). Diffusion-weighted imaging showed a small localized lesion in the median dorsal pons, and high-resolution T2-weighted imaging revealed slight left deviation of the lesion. It is predominately iatrogenic (treatment-induced), and is characterized by acute paralysis, dysphagia (difficulty swallowing), dysarthria (difficulty speaking), and other neurological symptoms. It occurs especially when the hemorrhage is in the pons area of the brain. Thus a CN7 palsy tends to coexist with a CN6 lesion despite the CN7 nucleus being in the lateral pons. The aim of the present study was to analyze the predictive value of clinical and neuroradiologic parameters concerning the outcome of patients with PPH. Stroke Sheryl Martin-Schild, MD, PhD, FANA, FAHA ... •Diverging eyes with fixed, dilated pupils (bilateral infarction of fibers of III) ... Pontine stroke syndromes Foville’ssyndrome •Paramedian branches of basilar artery, ventral and dorsal territories The part of the brain affected is the pons. Only one pupil will constrict if other areas of the brain has hemorrhage. CT Findings and Clinical Features as Markers for Patient Outcome These deeper structures receive their blood flow through a unique set of arteries. Inferior medial pontine syndrome, also known as Foville syndrome, is one of the brainstem stroke syndromes occurring when there is infarction of the medial inferior aspect of the pons due to occlusion of the paramedian branches of the basilar artery 1-3.This infarction involves the following 1-3:. Only one pupil will constrict if other areas of the brain has hemorrhage. Left lateral pons c. Left ventral pons d. Right ventral pons. In the emergency department, he was immediately connected to a respirator. The artery of Percheron was first described in 1973 by French Neurologist Gerard Percheron. The brainstem is composed of the midbrain, the pons, and the medulla oblongata, situated in the posterior part of the brain. Left dorsomedial pons b. 1980;11:84-90; Shin, SC et al. 17(2):55-7. . pupil (oculomotor nucleus), (B) Oculomotor nerve palsy. an analysis of 35 cases and research in prognostic factors. Kor J Cerebrovasc Surg. 2. Miosis in both pupils is a common symptom of an intracranial hemorrhage or a brain stem (Pontine) stroke. Neurophysiological testing in neurocritical care. 28 Guérit JM. The pons, midbrain and medulla ... Other autonomic functions (e.g. When the front part of the brain is affected both pupils become small but when other areas of the brain are affected one pupil dilates as the other constricts. [71] This case illustrates that physicians should be aware of the treatable condition of HE as a possible diagnosis in patients with bilateral pinpoint pupils and … These can happen with traumatic brain injury, stroke or illness. 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